About these reports

Using data derived from Beacon Checkpoint, The 2022 Checkpoint Landscape Review series encompasses three reports that provide valuable insight to the 2022 checkpoint and ICM landscape.

You will be given a complete overview of the existing ICM landscape (as of the 10th January 2023), an in-depth analysis of what happened in 2022 from a drug and trial perspective, and we will be sharing a full list of all notable regulatory announcements.

This three part series consists of:

  • The Drug Landscape – including an introductory brief overview of ICMs progress during 2022, followed by an in-depth analysis of the 2022 drug landscape.
  • The Trial Landscape – a deep dive into the 2022 trial landscape covering topics such as clinical trials initiated per year, phase distribution, recruitment status of ICM trials, and commercial developments.
  • 2022 Regulatory Announcements – this segment houses a complete list of regulatory announcements throughout 2022 and is categorized by drug name.

The 2022 Drug     Landscape   


The 2022 Trial     Landscape   


2022 Regulatory Announcements


The 2022 Checkpoint Landscape Review

The Entire 2022 Landscape Review


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Beacon Checkpoint

How the most complete Checkpoint database can help you

What we cover

Beacon Checkpoint is a sector-specific curated database that includes trial and drug records for preclinical, active, approved, and discontinued:

  • Immune Checkpoint Modulator Combinations
  • Immune Checkpoint Modulators Monotherapies
  • Across over 27 different checkpoint targets

How Beacon Checkpoint works

Use an intelligent search function to instantaneously sweep the clinical trial and drug landscapes using 20 search criteria including therapeutic class, target etc… Search for combinations in trials or individual arms to avoid false positives.

Key data points are presented in the results page and can be easily downloaded into Excel to run more complex analyses.

If publicly available, information regarding trials where an immune checkpoint is in combination with an antibody-drug conjugate, bispecific, cell therapy or gene therapy will also be included in our trial coverage.