About these reports

Using data from Beacon as of the 16th of January 2023, the following series provides an analysis of the existing Gene Therapy landscape, an overview of what happened in 2022, and a look at what the future might bring.

The four-part analysis is split into:

  • The Landscape Overview – An Analysis of the entire drug and trial landscape changes from H2 2022 to now.
  • 2022 Highlights – Highlights of the Gene Therapy (GT) collaborations, mergers, and acquisitions of 2022, as well as the regulatory announcements for GT assets.
  • Current Trial Landscape – A detailed review of the trial landscape broken down by change of status and phase and a review of assets which entered the clinic in 2022.
  • Enrolment Figures + 2023 and Beyond – A comparison of the actual and estimated enrolment figures for the main disease indications of each main gene therapy disease group*

*data only shows results from trials which have posted both actual and estimated enrolment figures.

The Landscape Overview

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Beacon Gene Therapy

How the most complete gene therapy database can help you

What we cover

We included trial and drug records for preclinical, active, approved, and discontinued:

  • RNA/DNA Viral vector-based therapies
  • DNA Non-viral vector-based therapies
  • Genetically Modified cell therapies
  • Empty Vector Trials
  • Other comparable modalities within gene therapy, whether cell-free or cell-based
  • Beacon Gene Therapy covers all genetically driven non-oncology indications that utilize gene therapy to mediate the condition.

How Beacon Gene Therapy works

Search the clinical trial and drug landscape by gene/mutation, editing technology (CRISPR/Cas9, Cas-CLOVER, etc.), gene delivery system, promoter, etc., instantaneously and/or extract the data points you need to conduct more complex analysis.

If publicly available, information regarding immunogenicity is included (unique to Beacon Gene Therapy).

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Beacon is the essential decision-support tool for developers of complex therapeutics. Our market-defining, proprietary ontologies, combined with the most accurate and comprehensive life sciences data, provide our customers with unparalleled visibility of the drug and trial landscape.

With Beacon, you can make drug development decisions with confidence. This is why 23 of the world’s top 25 drug developers trust us.

Discover a database tailored to your needs

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Our dedicated account and research teams can help you with questions by showing you how this insight and data is collated on Beacon.


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