Make Faster, Better, Drug Development Decisions

Beacon DDR Database

The most comprehensive DNA Damage Response (DDR) database available. Providing timely and accurate, market leading, preclinical and clinical DDR drug, trial, and commercial intelligence data

Beacon DDR Database Summary

  • Unrivalled comprehensive & accurate preclinical and clinical DDR drug, trial and commercial data.
  • Access to 800+ Drugs, 1,800+ Trials, 900+ Companies, and 600+ Deals in the DDR space
  • Market leading ontologies, enabling precise navigation of the DDR drug development landscape
  • Manually curated by DDR scientists, with data updated daily
  • Your one stop shop for DDR intelligence data

Why Beacon DDR Database?

Advanced Filtering

Drill down into Beacon’s DDR drug and trial data with a unique selection of >30 search filters. Segment the DDR drug and trial landscape to identify the data that matters most to you. Our filters include:

Drug Target

Drug Modality

Disease Indication

Repair Pathway

Formulation

Synthetic Lethality Info

Drug Status

Drug & Trial Milestones

Trial Phase & Location

How Beacon DDR Database Can Help You?

How can I monitor the next generation of DDR targets and understand the development stage of the drugs?

Leverage Beacon DDR’s unique searching ontologies to run the most accurate searches for DDR drugs & trials based on the target, repair pathway, synthetic lethality info, disease & phase, all tagged by a team of DDR analysts to remove the burden of keyword searching

How can I build a case for investors to show that a combination-based approach is as validated as a drug with single-agent activity?

Access all preclinical & clinical data for both single agent & combination therapies in one place, curated by our team of DDR analysts to the level of preclinical animal models, clinical toxicity, overall response, PFS & beyond, to quickly understand where your data differentiates with confidence

How can I track the combination agents being used for a given target & indication?

Use Beacon’s proprietary clinical trial searching filters to run highly targeted combination searches across DDR trials in combination with other modalities such as checkpoint modulators, with the ability to filter by biomarkers & key clinical readouts such as PK data, overall response, and progression free survival

Take advantage of our comprehensive modality tagging within Beacon DDR & our other datasets such as ADCs, Bispecifics, and Oncology to laser in on successful strategies & access curated clinical design data points.

How do I differentiate my pipeline & raise the vital capital to take our checkpoint drug to the next phase?

Bulletproof your DDR investment strategy by confidently communicating your position in the market to investors & potential partners, with well benchmarked science, allowing you to stand out in a competitive market using robust data from Beacon.

Beacon helps developers stand out by providing comprehensive insights into targets, diseases & combination strategies & enhances your ability to attract investors and secure the capital needed to take your DDR drug to the next phase.

How can I find the right partners in a competitive DDR market?

Optimize your DDR partnership strategy by identifying new prospect companies or competitors as soon as they enter the field, taking advantage of Beacon’s unique approach to capturing early-stage companies and curated insights on deals & pipelines all in one place.

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DDR Database: The Numbers

800 +
DDR Drugs
1,800 +
DDR Trials
900 +
DDR Companies
600 +
DDR Deals

Beacon DDR Database: Key Data Segments

Beacon DDR is a manually curated database of comprehensive, high quality, and accurate, preclinical and clinical drug, trial and commercial data, offering unrivalled insight into the DDR development landscape.

Drug Data

Revolutionize your searching of the DDR drug development landscape.

Utilize >20 search filters to find programs based on disease indication, drug modality, repair pathway, binding affinity, mechanism of action and many more.

Trial Data

Optimize your DDR clinical trial design searching capabilities.

Seamlessly benchmark clinical trial results and search the DDR trial landscape based on drug technologies, combination trials, trial locations, trial phase, disease indication and more.

Milestones

A unique DDR drug development milestone filter and visualization tool.

Track past, present, and future DDR drug development milestones, including drug and trial readouts, asset history, and regulatory announcements.

Company Data

Your centralized location for DDR company intelligence

Identify competitors and business development opportunities, using unique company filters including, company type, HQ locations, operating status & latest funding round, and technologies / diseases targeted in their pipeline.

Deal Data

De-risk your DDR drug development partnership & fundraising projects

Search DDR deals using custom search filters based on drug technologies involved, deal value & upfront payments, deal types to filter M&As, financing & partnership / licensing deals, geographic market, funding type, and many more.

Beacon DDR Database: Drug Modalities

Analyze 800+ drugs (preclinical and clinical) and 1,800+ clinical trials (from early to late stage).

Beacon DDR identifies drugs utilizing the concept of synthetic lethality, and covers DDR repair pathway components, including:

  • Damage Sensors
  • Signalling/Mediator Proteins
  • Effector Proteins
  • Cell Cycle Checkpoints
  • DNA Metabolism when in relation to repair and recombination

Several key therapeutic targets in the DDR landscape included in this dataset are:

  • PARP
  • ATM
  • ATR
  • CHK1/2
  • WEE1
  • DNA-PK
  • POLQ
  • WRN
  • PARG

Beacon DDR also includes a host of preclinical data including, cell line and animal model experimental data.

Who Is Beacon DDR Database For?

Beacon DDR is a manually curated database of comprehensive, high quality, and accurate, preclinical and clinical drug, trial and commercial data, offering unrivalled insight into the DDR drug development landscape.

Scientific Strategy Leader

Select the right pipeline for your DDR drug development

Research Scientist

Validate new targets & inform your DDR drug design

Clinical Development

Design optimized DDR clinical trials & benchmark against the competition

Business Development

Uncover new DDR drug licensing, partnership and fundraising opportunities

Competitive Intelligence

Track competitive threats & emerging DDR technologies

Translational Development

Confidently take your preclinical DDR therapy into the clinic

Related Solutions

Check out additional solutions available from Beacon

Related Resources

Check out DDR related resources available from Beacon

Real Life Customer Success Stories

“Beacon is a great database that people should pay attention to. It’s much better than many of the more generic databases that try to capture all data about everything”

Director
Top Biotech Company

Our Experts

Tejal Odedra

 

Lead Research Analyst

Charlie De Lanoy Meijer

 

Account Manager

Frank Plowden

 

Account Manager

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