The Bispecific Revolution Is Here
414 new drugs, 519 trial additions, and two first-time approvals in H1 2025 alone.
Our two-part Landscape Review series delivers an in-depth view of how the field is evolving, backed by real-time data, not speculation. Whether you’re tracking T cell engagers, scouting new deal activity, or benchmarking competitor progress, this report offers a clear, structured overview of the first half of 2025.
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What’s Inside?
The Drug Landscape
A snapshot of bispecific drug development in H1 2025, spotlighting new entries, key approvals, top targets and indications, plus the latest discontinuations and the reasons behind them.
The Trial Landscape
Monitor critical trial milestones – initiations, completions, and status changes, alongside insights into combination trials and scaffold-specific toxicity.
The Commercial Landscape
Deal trends by type and therapeutic class, comparisons with H1 2024, and a global overview of bispecific companies, including new entrants, and geographic spread.
Regulatory Announcements
A summary of H1 2025’s regulatory updates by type, plus a look at the drugs with the most regulatory updates.
The Future of the Bispecific Space
A forward-looking view of the field, highlighting key drug candidates to watch in the coming months, and trials expected to conclude by 2030.
Previous Bispecific Landscape Reviews

Bispecific 2024 Landscape Review

Bispecific H1 2024 Landscape Review
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Learn More About Bispecific
- The Most Comprehensive Way to Search the Bispecific Drug Development Landscape: Unique search ontologies based on Bispecific drug and trial characteristics
- Market Leading Approach to Bispecific Preclinical & Clinical Data Curation: Manual curation of key Bispecific research and development data points Bispecific research scientists
- Seamlessly Integrate Commercial & Scientific Data all in One Place: Search Bispecific company and deal data based on their pipeline and technologies.
- Unrivalled Granularity in Reports & Analysis: Our search ontology and technology indexing enable comprehensive analysis not seen elsewhere.
What is Beacon?
Beacon is a world leading data analysis tool for preclinical and clinical trial information. With unrivalled granularity of search function, data quality, and exhaustiveness, Beacon provides timely information and gives you confidence to progress your targeted drug therapies to patients.
Learn more about how our clinical trials and drug database solutions can be tailored to your research requirements