54 abstracts were focusing on Frontline therapies
  • 25% of the 54 are pivotal phase 3 trials with NSCLC making up the majority
  • Interestingly, Kidney Cancer has shown to report data on six pivotal trials

Despite the impact of the COVID-19 pandemic, majority of phase 3 trials remain active, 35% of them are associated with NSCLC, 27% of which are pivotal.

Distribution of Abstracts by Drug
  • The pivotal, phase 3 trial, SAUL, is making strides towards the treatment of bladder cancer as it is investigating multiples lines of therapies.
  • Pembrolizumab is associated with 50% of pivotal phase 3 trials. Will data from KEYNOTE-062 result in approval for Pembrolizumab as a frontline treatment for gastric cancer?

Key Learnings

Across the phases, clinical trials remain active or recruiting patients, thus showcasing the continual growth of the checkpoint landscape.

Majority of the trials are in phase 2 and 3. Are we on the verge of witnessing new approvals across multiple disease indications?

Interestingly, 10% of pivotal phase 3 trials are associated with kidney cancer. With numerous resources invested into this disease indication, are approvals on the way? How many approvals will we see and what impact will they have on the landscape?

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This insight and data is part of the subscription to Beacon Checkpoint.

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